Steroid Receptors and Their Roles in Pig Uterus
نویسنده
چکیده
This study reviews the roles of steroid receptors, mainly oestrogen receptor alpha (ERα) and progesterone receptor (PR) in pig uterine tissues with an emphasis on various stages of the oestrous cycle comparing to the time of early pregnancy. In addition, the secretory and proliferative activities under the influence of steroid hormones and their specific receptors were also documented. Some differences were found with respect to uterine compartments and physiological status of the uterus which indicated the different roles of these receptors in controlling reproductive functions. As both ERα and PR proteins were found in almost all cells of some tissues compartments, it indicated that the two receptors could be co-localized in the same cell and therefore the interactions of these steroid receptors were needed in order to regulate reproductive functions in the pig uterus.
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